Would you drink a beer with a vaccine?

Have you ever brought kids for vaccination? At least my young kids complain and cry even before the needle comes. My youngest last time that we brought her here, she cried, and we had to hold her. Interesting that when the needle comes in she just forgets about it. I feared needles as well in the past. I remember when I was suspected for having Dengue virus infection, I had to do a blood work. At the time I was a teenager and I got a bit of anxiety and that makes me remember how it was a bad experience for me. Nowadays, I don't have any problem with needles, but many adults fear them a lot.

That reminds me of one theory about how anti-vaccine feelings started to grow that could be associated to needles fear. Why don't we argue so much against existing/new medicamentation, but with vaccines, it looks like people start to do their best to find a comma or what if? Rare side effects are a reason for condemnation, while people take pills like they are eating candies. Maybe changing the routes of administration can reduce these anti-vaccine feelings in the population?
Maybe that's how a researcher, Chris Buck, from the National Cancer Institute in Bethesda, Maryland, thought about solving this problem. But maybe in a controversial way. Using an alcoholic drink like beer to carry viral proteins from polyomaviruses, which are associated with cancer and severe disease in immunosuppressed individuals. The idea is to use genetically engineered brewer’s yeast that he is brewing his beer with, a gene that encodes the protein VP1, which exists in the viruses. His group was testing an injected vaccine with this protein in India, but he decided to try this other route, like Polio and Rotavirus vaccines.
The idea is interesting, but how he works is a bit dubious; he decided to use himself and his brother as testers. Because of that, his institution blocked the self-experimentation and objected to how the results were shared, which made him do that in his home. So drank the vaccine beer at home with his brother. He tested himself after and noticed that he got antibodies to an extra two subtypes of polyomaviruses. But when trying to publish the results, the National Institute of Health (NIH) and other scientists were cautious about public dissemination of results that had not undergone peer review, since only two people are part of the testing cohort, in addition to the self-testing problem.

The scientist looks like he published his results in his blog as well, which is a type of revolt against the system. In my opinion, all these DIY science projects can be dangerous without enough testing. Nothing is too good to be true. Do we always find gold while walking in the streets? It is the same for cure and vaccine solutions. I know that people want to end all the problems in the world, but the things that we ingest need to be proven safe and effective. In an era where people are distributing Ozempic as the ultimate medicine, I wouldn't be surprised if they see some big problems with the long term usage of this drug. So despite of a vaccine in a beer being a good idea, maybe I wish to see more results on that.
You can check more about this story at Science Direct's article from December 19th, 2025 .


Você já trouxe crianças para vacinar? Pelo menos meus filhos pequenos reclamam e choram antes mesmo da agulha chegar. Da última vez que trouxemos minha filha mais nova aqui, ela chorou e tivemos que segurá-la. É interessante que, quando a agulha entra, ela simplesmente esquece. Eu também tinha medo de agulhas no passado. Lembro-me de quando suspeitaram que eu estava com dengue e precisei fazer um exame de sangue. Na época, eu era adolescente e fiquei um pouco ansiosa, o que me faz lembrar como foi uma experiência ruim para mim. Hoje em dia, não tenho nenhum problema com agulhas, mas muitos adultos têm muito medo delas.

Isso me lembra uma teoria sobre como o sentimento antivacina começou a crescer, que pode estar associado ao medo de agulhas. Por que não discutimos tanto contra medicamentos existentes/novos, mas com as vacinas, parece que as pessoas começam a fazer o possível para encontrar um coma ou algo do tipo? Efeitos colaterais raros são motivo de condenação, enquanto as pessoas tomam comprimidos como se estivessem comendo doces. Talvez mudar as vias de administração possa reduzir esses sentimentos antivacina na população?
Talvez tenha sido assim que um pesquisador, Chris Buck, do Instituto Nacional do Câncer em Bethesda, Maryland, pensou em resolver esse problema. Mas talvez de uma forma controversa. Usando uma bebida alcoólica como a cerveja para transportar proteínas virais de poliomavírus, que estão associadas ao câncer e a doenças graves em indivíduos imunossuprimidos. A ideia é usar levedura de cerveja geneticamente modificada, a mesma que ele usa para fabricar sua cerveja, com um gene que codifica a proteína VP1, presente nos vírus. Seu grupo estava testando uma vacina injetável com essa proteína na Índia, mas ele decidiu tentar essa outra via, como nas vacinas contra poliomielite e rotavírus.
A ideia é interessante, mas a forma como funciona é um tanto duvidosa; ele decidiu usar a si mesmo e ao seu irmão como cobaias. Por causa disso, sua instituição bloqueou o autoexperimento e se opôs à forma como os resultados seriam compartilhados, o que o obrigou a realizar o experimento em casa.Então, ele tomou a vacina de cerveja em casa com o irmão. Depois, fez o autoteste e percebeu que tinha anticorpos para dois subtipos extras de poliomavírus. Mas, ao tentar publicar os resultados, o Instituto Nacional de Saúde (NIH) e outros cientistas se mostraram cautelosos quanto à divulgação pública de resultados que não haviam passado por revisão por pares, já que apenas duas pessoas faziam parte do grupo de teste, além do problema do autoteste.

Parece que o cientista também publicou seus resultados em seu blog, o que é uma espécie de revolta contra o sistema. Na minha opinião, todos esses projetos científicos "faça você mesmo" podem ser perigosos sem testes suficientes. Nada é bom demais para ser verdade. Será que sempre encontramos ouro andando pelas ruas? O mesmo vale para curas e vacinas. Sei que as pessoas querem acabar com todos os problemas do mundo, mas as substâncias que ingerimos precisam ter sua segurança e eficácia comprovadas. Numa época em que distribuem Ozempic como a solução definitiva, não me surpreenderia se surgissem grandes problemas com o uso prolongado dessa droga. Portanto, apesar de uma vacina em forma de cerveja ser uma boa ideia, talvez eu deva esperar para ver mais resultados sobre isso.
Você pode conferir mais sobre essa história no artigo da Science Direct de 19 de dezembro de 2025.
Vaya, y habría posibilidad de sobredosis de cervecuna?
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I bloody hate needles too! If it was with a beee I'd definitely prefer it, or even just a pill... But if it's for severe diseases just better the needle than the disease
I don't enjoy needles, I just accept them lol and it is quick usually! I hate some pills also specially the big ones...sometimes it goes down bad
oh pills are easy, i always take big ones lol
Very interesting approach you give to such a sensitive topic. I agree with you that the fear is often mainly related to the procedure itself. The idea of administering vaccines orally can be innovative, but in my opinion there is still a lot of debate and research to be done. Great post, brother 👏