RE: I Finally Played The Binding of Isaac… and It’s Pure Chaos
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Although I haven't played it, something I liked about this game is that it has a system of synergies in the combination of items that is interesting and also the way to unlock certain playable characters, some even have a degree of difficulty too crazy.
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Oh yes, there are hundreds of items, many goes so well with others. I am trying yo unlock more characters, some have little challenges associated with them while some are just lovked behind a hidden secret that I have to figure out by experimentation, I think.